全文获取类型
收费全文 | 34020篇 |
免费 | 3664篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 205篇 |
儿科学 | 1093篇 |
妇产科学 | 964篇 |
基础医学 | 4813篇 |
口腔科学 | 697篇 |
临床医学 | 4100篇 |
内科学 | 6074篇 |
皮肤病学 | 546篇 |
神经病学 | 2992篇 |
特种医学 | 1401篇 |
外国民族医学 | 3篇 |
外科学 | 4381篇 |
综合类 | 752篇 |
一般理论 | 43篇 |
预防医学 | 4164篇 |
眼科学 | 878篇 |
药学 | 2573篇 |
中国医学 | 44篇 |
肿瘤学 | 1982篇 |
出版年
2021年 | 557篇 |
2020年 | 327篇 |
2019年 | 573篇 |
2018年 | 598篇 |
2017年 | 462篇 |
2016年 | 511篇 |
2015年 | 543篇 |
2014年 | 758篇 |
2013年 | 1134篇 |
2012年 | 1632篇 |
2011年 | 1595篇 |
2010年 | 933篇 |
2009年 | 835篇 |
2008年 | 1450篇 |
2007年 | 1531篇 |
2006年 | 1530篇 |
2005年 | 1464篇 |
2004年 | 1430篇 |
2003年 | 1339篇 |
2002年 | 1268篇 |
2001年 | 1185篇 |
2000年 | 1194篇 |
1999年 | 1023篇 |
1998年 | 389篇 |
1997年 | 352篇 |
1996年 | 320篇 |
1995年 | 292篇 |
1994年 | 326篇 |
1993年 | 317篇 |
1992年 | 813篇 |
1991年 | 779篇 |
1990年 | 767篇 |
1989年 | 666篇 |
1988年 | 689篇 |
1987年 | 642篇 |
1986年 | 594篇 |
1985年 | 656篇 |
1984年 | 531篇 |
1983年 | 415篇 |
1982年 | 263篇 |
1981年 | 274篇 |
1980年 | 250篇 |
1979年 | 460篇 |
1978年 | 340篇 |
1977年 | 255篇 |
1976年 | 269篇 |
1975年 | 251篇 |
1974年 | 285篇 |
1973年 | 261篇 |
1972年 | 268篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
12.
13.
A. Cattapan K. Browne D.M. Halperin A. Di Castri P. Fullsack J. Graham J.M. Langley B.A. Taylor S.A. McNeil S.A. Halperin 《Vaccine》2019,37(2):289-295
Introduction/Hypothesis
Recruitment of participants into phase 1 vaccine clinical trials can be challenging since these vaccines have not been used in humans and there is no perceived benefit to the participant. Occasionally, as was the case with a phase 1 clinical trial of an Ebola vaccine in Halifax, Canada, during the 2014–2016 West African Ebola virus outbreak, recruitment is less difficult. In this study, we explored the motivations of participants in two phase 1 vaccine trials that were concurrently enrolling at the same centre and compared the motivations of participants in a high-profile phase 1 Ebola vaccine trial to those in a less high-profile phase 1 adjuvanted seasonal influenza vaccine study.Methods
An online survey which included participants’ prior experience with clinical trials, motivations to participate (including financial incentives), and demographic information was developed to examine the motivations of healthy participants in two phase 1 clinical vaccine trials conducted at the Canadian Center for Vaccinology in Halifax, Nova Scotia. Participants were invited via email to complete the online survey. Readability and clarity were assessed through pilot testing.Results
A total of 49 (55.7%) of 88 participants of the two studies completed the survey (22 [55%] of 40 participants from the Ebola vaccine study and 27 [56.3%] of 48 from the adjuvanted influenza vaccine study). Motivations that were most frequently ranked among participants' top three in both trials were (1) wanting to contribute to the health of others, (2) wanting to participate in something important, (3) wanting to contribute to the advancement of science, and (4) wanting to receive an incentive such as money or a tablet.Conclusions/Recommendations
Although media attention and financial compensation were more often cited by Ebola vaccine trial participants as a reason to participate, both altruistic and self-interested factors were important motivations for participants in their decision to participate in a phase 1 vaccine clinical trial. 相似文献14.
Gary N. McAuliffe Susan L. Taylor Sharon Moore Joanne Hewitt Arlo Upton Anna S. Howe Emma J. Best 《Diagnostic microbiology and infectious disease》2019,93(3):203-207
Rotavirus vaccine has reduced disease prevalence in many countries. Consequently, we aimed to assess the reliability of a rotavirus immunoassay in the community population of Auckland and Northland, New Zealand. Between 22 October 2015 and 31 December 2016, 2873 fecal samples were tested by enzyme immunoassay (EIA, Rotascreen II, Microgen, UK) from 2748 patients (median age 8?years, range 0–101?years). Eighty-nine (3.1%) samples were reactive; 86 samples were tested by a second method. Rotavirus was confirmed in 49/86 (57%). Positive rotavirus EIAs were more likely to be confirmed in samples from cases ≥1?year of age (positive predictive value [PPV] 61%, 95% confidence interval [CI] 50–72%, P?=?0.049) and in spring/summer (PPV 67%, 95% CI 55–78%, P?=?0.003). Reactive rotavirus tests required confirmatory testing regardless of demographic, vaccine, or seasonal factors; a review of rotavirus testing algorithms may be necessary in other vaccinated community populations. 相似文献
15.
Y. Xin A. Davies L. McCombie A. Briggs C.‐M. Messow E. Grieve W. S. Leslie R. Taylor M. E. J. Lean 《Diabetic medicine》2019,36(8):1003-1012
16.
Daniel J. Robbins Natalie E. Taylor Damodaran Narayanan Aaron S. Hess William N. Rose 《Journal of clinical apheresis》2020,35(2):128-130
A 32-year-old male with type I diabetes presented with profound hypoglycemia due to exogenous insulin antibody syndrome in the setting of newly-diagnosed common variable immunodeficiency. Immunomodulatory therapy was not initially effective, but after the initiation of plasma exchange hypoglycemia resolved, and glucose lability improved. 相似文献
17.
Frederick R. Taylor MD FAAN FAHS Wade Cooper DO Robert G. Kaniecki MD 《Headache》2020,60(8):1857-1867
18.
19.
20.
Jerome Marley Julia Taylor Jane Brocksom Kath Schubach Andrea Nixon Paula Allchorne Susanne Vahr Lauridsen 《International Journal of Urological Nursing》2020,14(1):5-12
A series of three World Café events centred on the topic of developing an Educational Framework for Urological Nursing [EFUN] were held by the British Association of Urological Nurses [BAUN], the European Association of Urology Nurses [EAUN] and the Australian and New Zealand Urological Nursing Society [ANZUNS] between 2017 and 2019. About 376 urology nurses participated in these “conversations that matter” and generated 1047 individual response items that were grouped into themes to assist the three associations to take the creation of an EFUN to the next level. Areas explored centred on four aspects: what any agreed educational framework for urology nursing should contain; the academic level at which education should be provided; who should be recruited as collaborators on writing an educational framework and, lastly, just how any emergent framework should be used. Analysis of the conversational data indicate that there exists within the urological nursing community a collective wisdom regarding their educational needs and how these needs should be met. 相似文献